Coagulation Disorders & Thrombosis
SUB-STUDY

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This subgroup will focus on physiologic changes in COVID patients related to hemostasis and how these factors are associated with bleeding and thrombotic complications in COVID 19 patients. Use of anticoagulants and observed outcomes will also be explored.  Laboratory measures, administered medications, complications, bleeding and thrombotic events and interventions will also be tracked and evaluated. Associations with non-COVID patients if available or those with other viral diseases may also be investigated.

Patients may be investigated from early on in hospital or healthcare entry through the hospital to ICU and beyond. The subgroup will also work closely with the Neuro, ECMO and Immunology groups as projects may overlap. In collaborative centres that routinely perform rotational thromboelastometry (ROTEM) or thromboelastography (TEG) in their clinical practice, we will carry out an additional observational sub-study to appraise coagulation disorders and/or pro-thrombotic risks in COVID-19 patients in the ICU.

The impact of new monitoring schemes, devices and outcomes will also be assessed. Immunology related to hemostasis and observed outcomes in COVID 19 patients will also provide information as to the integration of these pathways on disease progression and outcomes.

How do I get involved?

  1. If you are interested in participating in this sub-study please contact the Principal Investigators:

    Coag-COVID Critical Contact:

    • Heidi Dalton: Heidi.dalton26@gmail.com  

    • Asad Usman: Asad.Usman@pennmedicine.upenn.edu

    • Yevgeniy Shek: y.shek@uq.net.au 

    • Declan Sela: declan.sela@gmail.com

  2. You will need to submit the COVID Critical Protocol to your IRB for approval. The protocol is available here.

  3. Email your IRB approval/amendment document to ECMOCARD@health.qld.gov.au and Chloe will arrange REDCap access to the sub-study fields.

CURRENT SUB-STUDIES

Data collected from the COVID-Critical study will also be used to in a series of studies focusing on a wide range of areas.

 

NEUROLOGICAL SUB-STUDY

NEUROLOGICAL
SUB-STUDY

CARDIAC SUB-STUDY

CARDIAC
SUB-STUDY

COAGULATION DISORDERS & THROMBOSIS

COAGULATION DISORDERS & THROMBOSIS

ACUTE KIDNEY INJURY

ACUTE KIDNEY
INJURY