BMJ publishes landmark COVID-19 paper
“This paper is one of the most important recent studies in our field and sets a precedent for the way observational data can be rigorously evaluated and disseminated.”
Professor Daniel Brodie
President-elect, Extracorporeal Life Support Organization (ELSO) and Chair of the Executive Committee of the International ECMO Network (ECMONet)
Figure 1
Treatment with extracorporeal membrane oxygenation (ECMO) if ratio of partial pressure of arterial oxygen to fraction of inspiratory oxygen (PaO2/FiO2) was <80 mm Hg, was compared with treatment with conventional mechanical ventilation without ECMO. Adherence adjusted estimates are reported for differences in hospital mortality and probability of hospital discharge alive in 7345 patients with covid-19 associated acute respiratory failure. Shaded areas represent 95% confidence intervals
Figure 2
As treated analysis in 7345 patients, with hospital mortality compared between treatment as received, which could have included treatment with extracorporeal membrane oxygenation (ECMO), and treatment with conventional mechanical ventilation without ECMO. Shaded areas represent 95% confidence intervals.
Figure 3
Treatment with extracorporeal membrane oxygenation (ECMO) if ratio of partial pressure of arterial oxygen to fraction of inspiratory oxygen (PaO2/FiO2) was <80 mm Hg compared with conventional mechanical ventilation without ECMO. Adherence adjusted effects (95% confidence intervals) on hospital mortality within 60 days reported by age groups and baseline comorbidities.